Prelude: Index, Introduction.
Chapter One: The psychoactive Legumes.
Anadenthera: introduction/botanical description/History/Preparation and ingestion/Chemistry and extraction/Bioassay
Mucuna: introduction/botanical description/History/Preparation and ingestion/Chemistry and extraction/Bioassay
Mimosa: Hostilis, scabrella
Chapter Two: The others
Virola: introduction/botanical description/history/preparation and ingestion/chemistry and extraction/bioassay
Bufo Alvarius Toads:1
Cultivating the allie
The Bufotenin controversy
Quick Reference: Chemical Properties/trypamine chemistry/nomenclature/Plants reported to contain tryptamine/references
The Following information is for educational purposes only. Ingestion or preparation of the following plants might be considered illegal in most countries. The plants mentioned here are very powerful and should be treated with much respect and care.
?POW, BAM, BONG?.. I start to see exploding colored stars as if I was being quickly jabbed on the face by a heavy handed box fighter?
??.don’t do this if you’re afraid of ghosts?
There exists many plants that contain a usable amount of psychoactive Tryptamine and related alkaloids. For centuries these plants have been utilized by different cultures for their entheogenic effects. This discovery is relatively new and there is still much information to be uncovered. The cultures that use these plants are slowly becoming wiped out. The ritualistic utilization of Anadenanthera seeds in south America dates back at least 4,500 years.
The Leguminosea family is also known as the Fabisea or pea family. It consists of about 18,000 species in over 650 genera. Legumes are widespread on all habitable continents. There are many known psychoactive plants in the pea family. Acacia, Anadenanthera, Desmodium, Mimosa, and Mucuna are just a few known entheogens in this family.
Acacia is another member of the leguminosae family. The leaves and bark contain tryptamine. In Australia there are more than 700 Native species of Acacia. Acacia has played a large role in the Australian culture. There are reported to be tryptamine in the following Acacia species: Albida, Confusa, Cultriformis, Laeta, Mellifera, Nilotica, Phlebophylla, Podalyriaefolia, Polyacantha, Senegal, Seyal, Sieberiana, Simplicifolia, Vestita.
The genus Anadenanthera, a member of the leguminosae family, has been used for its psychoactive effects for approximately 4,500 years. The seeds and seed pods are known to contain several tryptamine alkaloids including Bufotenine, 5-meo-DMT and N,N-DMT. The bark is also thought to contain alkaloids but there are no records of its usage.
Identification of the Anadenanthera species can be difficult as there is much misinformation regarding them on the internet and in literature. A. Colubrina includes two subspecies including A. Colubrina Var. Colubrina and A. Colubrina Var. Cebil. A.C. Var. Cebil has seeds that are more rounded and thin whilst A.C Var Colubrina has seeds that are Square, Fat, and brown-red in color.
The genus includes Anadenanthera Colubrina, A. Macrocarpa, and A. Peregrina. The species can be difficult to tell apart as they look very similar. They both have dark blackish bark, conical thorns, white flowers, and dark seed pods. A. Colubrina grows 9-50 feet tall while A. Peregrina may attain a height of 65 feet.
The seed pods of Anadenanthera Colubrina are flat, dark brown in color and grow up to one foot long. They appear to be leathery but feel like plastic. They can contain as many as 14 seeds per pod. The dry pods rattle with seeds when you shake them. After the pod dries is splits open and releases seeds. The seeds are flat, rectangular with rounded angles, colored brownish red in the center and fade into a darker shade on the edges. They are between 1-2cm wide usually averaging out at 1 1/2 cm. A. Colubrina contains a high amount of bufotenine. One sample of seeds acquired from Argentina contained 70% bufotenine, 20% 5-meo-DMT, and 5% n.n-DMT. Per every gram of seeds their contained 10-20 mg of tryptamine. The seed pod itself has the same alkaloid content as the seeds do. Anadenanthera Colubrina is native to northwest Argentina. Synonyms for A. Colubrina include Piptedenia Colubrina, Anadenanthera Columbrina.
The seed pods of A. Peregrina are rough and woody. They may contain from 3 to 10 seeds in a pod. The round seeds are flat, thin, and glossy black in color. Anadenanthera Peregrina is native to the tropical zones of South America and the West Indies. It is found throughout Northern South America. The seeds of A. Peregrina contain mainly n,n-DMT and 5-meo-dmt. Piptedenia peregrina and Acacia Niopo have been used as synonyms for Anadenanthera Peregrina.
Although the two species are very similar they have a different historical background.
Anadenanthera Colubrina was traditionally used by the Shamans of the southern region of the Andes. The seeds are made into a snuff called Cebil or Vilca.
Anadenanthera Peregrina is used in the Orinoco basin. It is cultivated by shamans because it is not native to this area. It is made into a snuff, under the name Yopo. The Yanomano and Waika tribes use it in Epena, a snuff containing A. Peregrina seeds, plant ashes, and other substances. It was traditionally used in the West Indies as a snuff called Cohoba, though this use was eradicated.
There are many ways to prepare and administer Anadenanthera. It is best to prepare between one and two grams of seed at a time. One gram usually amounts to 6-8 seeds. This should yield enough product for several excursions. Traditionally the seeds where roasted. One may place the seeds on a cookie sheet and roast them in the oven. Another way of preparation is to place them in a frying pan and fry them until the centers are dried and crispy. Be sure not to get the seeds to hot as excessive heat may quickly destroy the active constituents. Using the lowest heat setting is advised. The seeds will have a smell resembling cooked pumpkin seeds. As they continue to cook seeds begin to pop. Sometimes they shoot up into the air, so watch out. One objective of roasting the seeds is to void them of all water. The tryptamine are not soluble in water so this may be a primitive way of purifying the seeds. It may be possible to use a food dehydrator. After the seeds have been “cooked” Wait for them to cool. Many suggest removing the seed coat, It is a very laborious and annoying task but will make insnufflation easier. Ground the seeds up as fine as possible in an electric coffee bean grinder. The finer the powder the easier it will be on your nasal cavity.
The mineral lime(edit: Ca(OH)2 ) is added to the powdered snuff. Lime is slightly basic and DMT is soluble in alkali therefore this may be another step of the primitive purification process. It may be obtained from calcinating snail shells. Lime can also be purchased for around $3 an ounce at a science supply store. The right amount of lime is a crucial part of making snuff. Add 1/4 the amount of seed. So that would be 250mg CaO per One gram Powdered seed. Mix this up thoroughly. If lime is not available it may be possible to utilize baking soda. It is reported that using burnt sweet potato peels as a lime/baking soda substitute works well.
Chemistry and Extraction:
The three primary chemicals in anadenanthera are Bufotenine, 5-methoxy-DMT, and N,N-DMT. Other tryptamine including: 5-meo-MMT, DMT-n-Oxide, and 5-OH-DMT-n-Oxide where isolated aswell. There where even amounts of ringed tryptamine derivatives found (1,2-dimethyl-6-methoxytetrahydro-B-Carboline) which would mean MAO Inhibition. Ones main objective would be to isolate N,N-DMT from the snuff to avoid the overwhelming nature of 5-meo and bufotenine. There are many ways to extract tryptamine from the seeds. One needs to familiarize themselves with the properties of the psychoactive constituents.
Bufotenine(C12H16N2O) has a melting point of 146-147 C. It’s freely soluble in alcohol and less soluble in ether. It is also soluble in Diluted acid and alkali. It’s insoluble in water until it is converted into a salt. Bufotenine is converted into a salt by extracting it with a diluted acid. Once in its salt form its insoluble in non-polar solvents and soluble in alkali.
Effects: The effects of bufotenin.
N,N- Dimethyltryptamine(C12H16N2) has a melting point of 44.6-44.8 C and a boiling point of 60-80 C. Since it has a lower melting point than bufotenine it may be possible to use a distillation setup to extract the DMT but leave the bufotenine behind. N,N-DMT is Freely soluble in diluted acid and is insoluble in water. Once extracted with acid and converted to salt it is insoluble in Non-Polar Solvents but soluble in H2O and Alkali. DMT has a natural PH of 8.68 When extracting salts with a base try to bring it to its original pKa.
Effects: The effects of n,n-DMT.
Effects: The effects of 5-MeO-DMT.
Subject A’s first account with the snuff was prepared with 1.1 gram of finely powdered, roasted Colubrina seeds and a pinch of lime. He managed to insufflate one half of the powder. Immediately his sinus’s began reacting. After about one minute he received a sudden rush and pressure towards the head. This was followed by an intense change in consciousness. He felt very warm and heavy, almost in a narcotic stupor. This lasted for nearly 5 minutes then began to fade away.
The snuff creates a very intense effect. Try to insufflate as much as possible in a short amount of time.
The follow is an account with Anadenanthera Macrocarpa seeds.
?After I have my snuff ready, after spending lots of time and effort
cooking, grinding this stuff it’s time to finally try it for the first time.
I have always found nasty the act of snorting powdered substances but this is a
whole different thing… I tear a small piece of paper and roll it and then i
manage to snort my pre measured doses (not too little, not too much in order not
to sneeze). I said doses because I’ve administered it in both nasal cavities.
It flows in more or less well (it flows, not that it isn’t harsh) and
immediately I start to feel a very strong heat wave and i feel the sweat drops
starting to build up all over my forehead and then i sit down.
A tiredness (muscle relaxation?) wave came down from my head to the extreme of
my limbs, making me feel very very lethargic. By this time some abstract ideas,
concepts and mild visions came up but didn’t last very long.
After that I have recovered in a matter of minutes of the lethargic state.?
?After some other experiences I think I am now making a better snuff, taking more
care about it’s roasting point (it’s easy to under or over roast them – the
Under roasting is correctable at least). Now I am also peeling them after roasting.
Would it be possible to peel beforehand? Could be easier… Anyways, it’s always
a laborious task… let’s see if it’s worth…
Ok, after grinding well and sifting the stuff with a stretched cloth, it’s time
to administer this very thin powder that easily floats in the air…
One nostril at a time (I’d like to have the Y straw) and then POW, BAM, BONG!
Along with the usual sweating and heat feeling i start to see exploding colored
stars as if i was being quickly jabbed on the face by a heavy handed box fighter
or something. Wow. I manage to sit automatically… The relaxation wave on my
limbs was much stronger this time, damn, this batch is much stronger than my
other ones, I’m having progresses. I lay down in a semi dark room with my eyes
closed and experience the complete lack of thoughts. It was a bit scary at first
but I found it was boring after a while. Slowly i start to sink in the
drowsiness and i start to have some cool abstract thoughts and ideas, the visual
part is very mild but definitely present. I don’t remember well if i snorted
again, all I remember is that i felt very sleepy and ended up crawling to my
bed. No hangover, actually I felt quite better than usual in the following day
This is a report of the combination of Macrocarpa and Acacia Polyphylla
?Regular preparation + unpeeling, my standard now.
It took me well about 4 or 5 hours of work in the middle of the night and i was
already tired of the lethargic highs so i wasn’t expecting much out of this. I
decided that if i didn’t break through this time i would quit trying it.
Then i went, macrocarpas first. Feel good hit… strong ‘jabbing’ on my eyes,
strong waves through my limbs. I felt as though I would melt like plastic.
A nice letargo follows with the usual abstract thought patterns and the
mild visions, which sometimes happen to bind to my imagination or to the
concepts that come to my mind… Very cool i thought, stronger than ever but not
really a breakthrough.
I’ve lost track of the time enjoying this like i never did (with yopo) and about
45 minutes after i took the macrocarpas i went to the bathroom and cleaned up my
nose and sinuses, getting ready to try the polyphyllas.
And so I did.
The usual heating and flashes were felt but it was somewhat less painful than
with macrocarpas. Soon a very pleasant letargo took over and i laid back in the
dark. By this time the imagery that was mild with the macrocarpas started to
fuse with the abstract ideas i was experiencing and it developed to the point i
started to see sequential slides of bizarre things. They were some kind of
machinery or industrial machines but they were too odd in appearance because
they would combine the most different designs together, some aerodynamic parts
like 50’s cars, wheels on one side and things like Greek columns in the other,
along with all sort of non related crap all around it. It’s hard to describe.
The slide sequence has finally subsided and at despite of my lack of thoughts
(typical) i was feeling very WOW!.
By then I’ve opened my eyes, feeling really tired all i wanted was to sleep, but
hey, very cool colored visuals with open eyes, specially in the darkest parts of
a dark room. Then i was suddenly hit by a strong feeling of presence. I am very
used to that, Jane does it to me all the time but this time it was very strong a
bit scary. I am a well tripped guy, I usually wouldn’t fear entities or dead
people but it was really solid. I said fuck that, ignored it, went to bed and
had a great sleep. I felt great after I woke up but the presence thing kept
teasing my mind for a week long… ?
ORAL with MAOI:
The thought of using Anadenanthera orally with an MAOI is astounding. It would be an easy to ingest form of an ayahausca analogue that could easily be encapsulated. Unfortunately our results did not prove it to be a very good ayahausca candidate. The physical distress caused by the bufotenine was overwhelming. Including mental confusion, vertigo, headache, and vomiting.
Subject A held approximately 100mg of the snuff between his gums and cheek for 5 minutes with no noticeable effect. I imagine that more is needed to experience profound psychoactive effects.
Many people claim that smoking the seed or the snuff itself has psychoactive effects.
Further investigation on Cebil Bark needs to be carried out. There are reports of psycho activity.
There are several varieties of Mucuna. Here we will discuss Mucuna Pruriens. Mucuna Pruriens is also called cowage, cowitch, velvet bean, and Pica- pica. It is very possible to cultivate large amounts of this plant for harvest. Possibly for extraction purposes.
Mucuna, another member of the legume family, is a climbing plant that grows up to 30 ft. in length. It forms compound leaves that grow 4-10” long and is composed of three leaflets. The pods contain 2-5 per cluster and grow 2-3 inches long. Each pod contains 3-6 large black seeds. The pods have barbed hairs, also called trichomes, that cause an intense stinging irritation to the skin. It is a very prolific and hardy plant in the south.
The plant has many traditional and medicinal usage including treating abdominal pain, cholera, diabetes, infertility, Parkinson?s disease, scorpion bites, snakebites, and toothache. The large amount of Levo-dopa in the seed makes it great for treating Parkinson?s disease. It has been used as a food crop for grazing animals. It has also been used as an alternative food source.
Preparation and Ingestion:
It is reported that small doses of the seeds cause an increase in motor activity and a decrease in sleep time. Higher doses, three times that of a clinical dose, are reported cause a decrease in motor function and an increase in sleep time. It is said that one cigarette sized joint made of the leaves produces a strong CNS stimulation and a pulsing tryptamine buzz. There are many ways one may administer the beans. Insufflations and oral administration are the most common. It is reported that the beans are used as a coffee substitute.
Chemistry and Extraction:
Mucuna contains varying amounts of Tryptamine alkaloids including Levodopa and N,N-DMT. Different sources report different contents. None the less, this author is completely convinced that it is not void of useful compounds.
I believe one could make use of this as a daily ?tonic?. The aphrodisiac properties are appearant.
100mg of seed powder was insufflated and a slight CNS stimulation occurred.
Roughly 100mg seed powder snorted. Stimulation. Noticeable shift in consciousness.
It is well known that Mimosa Hostilis, as called jurema, contains high amounts of Dimethyltryptamine. It is used as an Ayahausca Analouge and as a source for extraction. It is reported that Mimosa Scabrella Seeds contain Tryptamine as well. Mimosa Pudica, also known as Sensitive Plant, is easily available and thought to contain trace amounts of tryptamine.
50 Mimosa Scabrella seeds were toasted at 150F for 15 minutes to void them of all moisture. The roasted seeds where powdered and a green color powder resulted. Roughly 1/4th, the total amount, Calcium Oxide was added. The powdered turned a light green and grey color. Two small piles were snorted. No dominant effects resulted. Pupils dilated.
Virola is in the Myristicaceae family.
Preparation: Powder the bark, Boil it down to a gummy tar, add Lime and Baking soda, Freeze it. Powder it. Snuff it.
Bioassay: The powder is very fine. Much more fine than Anadenanthera. The bark smells very spicy. It is very easy to insufflate. Around 100mg powdered extract with lime was snorted. No immediate effect. But after 2-3 minutes effects become noticeable. An alteration of consciousness and very warm feeling.
Bufo alvarius Toads:
The Bufo alvarius toad, also known as the Colorado river or Sanoran desert toad, is a producer of 5-methoxy-dimethyltryptamine.
Cultivating the allie
The Bufotenine Controversy
Bufotenin is classified as a Schedule one Hallucinogen. Shulgin?s experimentation with intravenous administration of bufotenin proved that bangin? the B is not the most enjoyable experience. His symptoms included many of the same characteristics of the snuff including pressure in fact and chest, Nausea, burning sensations in the face, seeing colored spots and dots, and heat flashes. So why would one consider this to be an entheogenic experience? The tribes of South America have been using this for thousands of years for spiritual purposes. They refer to it as the seeds of civilization or the beans of the Hekula spirit.
:Charts and Quick Reference:
Melting Point: 146-147 C
Boiling Point: 320 C
Insoluble in H2O
Less soluble in ether
Soluble in Diluted acids and alkali
Freely soluble in alcohol
Soluble in H2O
Soluble in Alkali
Insoluble in Non-polar organic solvents
Prismatic Crystals from hexane, MP: 67.5 68.5
Oxalate, MP: 173
Picrate, MP: 175-176
Methiodide, MP: 183
Melting Point: 44.6 – 44.8 C
Boiling Point: 60-80 C
Freely Soluble in diluted acids
Insoluble in H2O
Insoluble in non-polar organic solvent
Soluble in H2O
Soluble in Alkali
Chemical Nomenclature/Alternative names
KNOWN ALKALOID CONTENT OF ANADENANTHERA:
Alexander Shulgin was right when he said that “DMT is everywhere”. Not only do we produce it indigenously in our bodies, it occurs abundantly throughout nature. The following is list of plants that are known to contain Significant indole/tryptamine alkaloids.
desmodium: gangeticum, pulchellum, triflorum, caydatum.
Mimosa: Hostilis, Scabrella, Pudica
mucuna: Pruriens (Velvet bean)
Arundinella hirta (Reed Grass)
avena sativa (Oats)
festuca arundinaceous (Reed Fescue)
limonia acidissima (elephant apple)
Phalaris: Aquatica, arundinicea, canariensis, tuberosa (canary Grass)
Phramites Australis(arundo donox)
psychotria virids (chacruna)
oryza sativa (rice)
zanthoxylum: arborescens procerum
zea mays (corn)
Alkaloid: A basic organic compound of plant origin. Alkaloids are amines. Most have complex chemical structures of multiple ring systems.
Nitrogen Fixation: Root Nodules of Legumes contain bacteria that take atmospheric nitrogen and convert it to a chemical fertilizer form that enriches the soil.
The merck index
Ayahausca Analouges, Dekorne
Plants of the Gods 2nd edition, shultes, hofmann, ratsch
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- May 30, 2008 / 1:11 am